“Price Street corner York Lane,” Savannah, Georgia, 1939 or 1944, by Frances Benjamin Johnston, via Library of Congress Prints and Photographs Division.
The Library of Congress catalogue entry for the image above includes the note: “Once in the ‘Restricted District,’ hence the lattice work” — meaning the house had been a bordello. (That would also explain the panel of shutters across the front.)
Looking at Google Maps street view, a very similar house (built 1828) at one of the four possible corner sites still stands in good condition. Across York Lane from it is a two-story building that was probably there at the time of the photo. There are new condos on the other side of Price Street.